OswaldSchmiedeberg (1838-1921), a Baltic German pharmacologist, was born at GutLaidsen in the Imperial Russian province of Courland. In 1866 he earned hismedical doctorate from the University of Dorpat with a thesis concerning themeasurement of chloroform in blood. In 1872 he became a Professor ofPharmacology at the University of Strasbourg, where he remained for the next 46years. He is recognized as the "father of modern pharmacology". Hiswork primarily dealt with finding the correlation between the chemicalstructure of substances and their effectiveness as narcotics.

Overview:The Department of Pharmacology, established in 1967 under Dr.Mrs.C.K.Thampai,was headed by doyens like Dr.Vijayasekaran, Dr.Kanagambal & Dr.Vamsadhara.We are presently a postgraduate department with an well structured graduate program, systematic postgraduate training with special emphasis on clinicalpharmacology. The Pharmaco-vigilance pursuit of this department has been wellreceived across various clinical departments of the affiliate hospitals. TheDepartment has a well nursed animal research unit and a Museum that depicts theHistory of Medicine.
















Through the academic sessions 2011-2012 the Department was busy with seminars & sessions on

  • Research Methodology,
  • Drug Treatment in Migraine
  • Molecular Pharmadynamics in Cancer Chemotherapy
  • Nano-Pharmacy of Skin Diseases
  • Pharmacovigilance
  • Treatment of Malaria
  • Drugs in Tuberculosis
  • Management of Epilepsy
  • Treatment of Snake Bite.

ACADEMICS - GRADUATE PROGRAM: The Department has a well organizedGraduate Programme with academic postings during the 3rd, 4th and 5thsemesters.The Graduate Program includes basic training in Pharmacogenetics,Pharmacogenomics, Pharmacoepidemiology, Toxicology, Theoretical Pharmacology,Dosology, Pharmacognosy, Medicine development and safety testing, Druglegislation and safety, Clinical pharmacology, Neuropharmacology,Psychopharmacology, Behavioral Pharmacology and Environmental Pharmacology.

ACADEMICS - POST GRADUATE RESIDENCY PROGRAM: Graduate Program with two MDscholars taken in, every year under selection from the government of Tamilnaduand affiliated to the TN Dr MGR Medical University, Chennai. The academictraining includes Pharmacogenetics, Pharmacogenomics, Pharmacoepidemiology,Toxicology, Theoretical Pharmacology, Dosology, Pharmacognosy, Medicinedevelopment and safety testing, Drug legislation and safety, Clinicalpharmacology, Neuropharmacology, Psychopharmacology, Behavioral Pharmacologyand Environmental Pharmacology.The Postgraduate Program also includes a seriesof predetermined symposia, seminar, Journal Clubs, Lecture Sessions, Casediscussion, Pharmaco-Vigilance Audit and Medical Audit Meet. The residents alsoinvolve in training Pharmacology and Therapeutics to students of graduatemedical students. The residents train in our department to Independently planand undertake research related to drugs (basic as well as ClinicalPharmacology) and communicate the findings in conferences / journals, Set uptherapeutic drug monitoring, ADR monitoring, therapeutic audit and druginformation services, Plan and conduct toxicity studies and clinical trials, Educatethe public about use and misuse of drugs, Supervise breeding and upkeep ofsmall laboratory animals and mature as medical advisor in a hospital orpharmaceutical house.

The Course : Pharmacokinetics, Pharmacodynamics, Adverse Drug Reactions,Drug Interactions, Pediatric Pharmacology, Geriatric Pharmacology, Drugs inPregnancy and Lactation. Dosage calculation in special situations, Factorsmodifying drug action, Pharmacogenetics, Drug delivery systems and Fixed dosecombinations, Gene therapy, Sources of drugs. Principles of Toxicology,Principles of prescription writing.

Systemic Pharmacology, Chemotherapy and Therapeutics: Pharmacology ofdrugs acting on autonomic, peripheral and central nervous systems;cardiovascular, endocrine, respiratory, renal, gastrointestinal andhematopoietic systems and treatment of diseases affecting these systems;Pharmacology of anti-microbial and anti-parasitic drugs and treatment ofinfective diseases; cancer chemotherapy, immuno-pharmacology and ocularPharmacology, Dermatological pharmacology vitamins, Heavy metals andantagonists, Miscellaneous.

Experimental Pharmacology, Bioassay: Experimental methodologies involved in the discovery of drugs (in vivo, in vitroex vivo), animal handling and care, methods of anesthetizing animals andmethods of euthanasia, restraining and blood collection methods. Drug screeningmethods involved in the evaluation of anti-ulcer, antidepressant, anti-anginal,anti-hypertensive, anti-arrhythmic, anti-diabetic, anti-cataract,anti-platelet,ticancer, anti-inflammatory, anti-diarrheal, anti-epileptic,analgesic, anti-thyroid, antipyretic, anti-glaucoma, anti-hyperlipidemic,anti-asthmatic drugs and cough suppressants. Drug screening methods used inscreening anti-fungal, ante-helmenthic, antibacterial and antiviral agents.Drug screening methods for heart failure, posterior pituitary, adrenal, steroid(gluco & mineralo), testicular, parathyroid, ovarian, thyroid hormones,Methods involved in testing teratogenecity, carcinogenicity and organtoxicities in animals. Bio-assay and dose response relationship.

Clinical Pharmacology and Biostatistics: Principles of therapeutics,Individualisation of drug therapy, Drug regulatory systems, Placebo, Drugdevelopment, Pharmacoeconomics, Pharmacoepidemiology, Therapeutic drugmonitoring, Ethics of clinical trial, Ethical committee, Drug utilizationstudies, Essential drug concept and rational drug use and patient compliance.


TheDepartment has a central animal house under its aegis with 130 laboratoryanimals with facilities for breeding, intervention studies and trials. The research protocols under study in the department include.

  • A Comparative Study of the effects of amlodepine and S amlodepine in patients with mild hypertension
  • A study of the efficacy and safety of ivermectin, permethrin and GBHC in patients with scabies
  • Efficacy and safety of Deflazocort in patients with nephrotic syndrome
  • A Comparative study of supplementation of Zinc probiotics in children with acute diarrheal disease
  • Antibiotic sensitivity patterns in patients with Urinary tract infections at TVMCH
  • A study of the prescription patterns in the Dermatology Outpatient Department of TVMCH
  • A study of incidence and prevalence of Depression in patients on Antihypertensive Treatment
  • Antibiotic sensitivity patterns in neonates with septicemia at TVMCH
  • A study of incidence and prevalence of adverse drug reaction in patients on Antihypertensive Treatment
  • Pharmaco-vigilance in the Department of General Medicine at TVMCH
  • A study of the clinical effects of single dose gabapentin as postoperative analgesia
  • A study of the awareness of Pharmaco-vigilance among the medical faculty and professionals at TVMCH


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