::Departments : BASIC MEDICAL : BIOCHEMISTRY

FACULTY OF CLINICAL BIOCHEMISTRY

   

 

Carl AlexanderNeuberg (1877-1956) was an early pioneer in biochemistry, and often referred to as the "Father of Biochemistry". He was the first editor of thejournal Biochemische Zeitschrift. This journal was founded in 1906 and is nowknown as the FEBS Journal. Neuberg born in Hanover, worked on solubility andtransport in cells, the chemistry of carbohydrates, photo-chemistry,classifying different types of fermentation and study of the chemistry of aminoacids and enzymes

 

MESSAGE OF THE CHAIR


Dr.M.Saradha: The Department of Biochemistry ismarking 46 years of excellence in teaching & clinical service with exciting new areas to celebrate. The broad canvas of our department includes extensive facilities and new equipment for diverse biochemical tests with an associated continuous research effort. The Department of Biochemistry & Cell Biologyprides itself on its commitment to excellent teaching - fresher seminar introducing our graduate students to world of biochemistry and research, to acquaint them with the opportunities and experiences available to them at the beginning of their academic career. This also allows the student to take better advantage of their options and acquire a wider range of experience. We welcome new students to join us.


Succession of Heads of Departments
  Dr. Valmikinathan M.D 1967 - 1971
  Dr. Padma Ramamoorthy M.D 1971 - 1990
  Dr. Sheik Mohammed M.Sc, Ph.D 1991 - 2000
  Dr. Abdul Subhan M.Sc, M.B.B.S 2000 - 2005
  Dr. M. Saradha M.D 2005 - 
 
CLNICAL BIOCHEMISTRY SERVICES
BASIC BIOCHEMISTRY: The Department has a dedicated CLINICAL CHEMISTRY lab service for all material received from the OPD and wards of TVMCH and other affiliate hospitals. The laboratory has automated processing systems and undergoes quality assurance reviews between the biochemists. This unit of our department is the stand alone referral unit for government run hospitals in the southern region of State of Tamilnadu. This lab works 24x7 with a team of dedicated technicians.
ENZYMOLOGY: The Department has a fully deployed Clinical Enzyme Chemistry unit in the TVMCH for patients being seen at the affiliate hospitals. All areas of Clinical studies including: 15 major enzyme studies. The lab routinely undergoes quality assurance reviews with EQAS programs. The laboratory has a Automated ELISA System. This lab works 24x7 witha team of dedicated technicians.
ENDOCRINOLOGY: The Department has ENDOCRINOLOGY service easily accessible for patients being seen at the TVMCH and other affiliate hospitals for study of thyroid etc. The lab routinely undergoes quality assurance reviews with EQAS programs. The laboratory has automated ELISA System.
S. No Year Clinical Biochemistry
1. 2005 213908
2. 2006 263386
3. 2007 292644
4. 2008 362593
5. 2009 432686
6 2010 508012
7 2011 592216

GRADUATE ACADEMIC PROGRAM: Biochemistry includes Medical Physics and Molecular Biology. The broad goal of the teaching under-graduate students in bio-chemistry is to make them understand the scientific basis of the life processes at the molecular level and to orient them towards the application of the knowledge acquired in solving clinical problems. At the end of the course, the student shall be capable to:
  • Describe the molecular and functional organisation of a cell and its sub cellular components; Delineate structure, function and inter-relationship of biomolecules and consequences of deviation from normal; summarize the fundamental aspects of enzymology and clinical application where in regulation of enzymatic activity is altered.
  • Describe digestion and assimilation of nutrients and consequences of malnutrition; Integrate the various aspects of metabolism and their regulatory pathways; Explain the biochemical basis of inherited disorders with their associated sequel; Describe mechanisms involved in maintenance of body fluid and pH homeostasis; Outline the molecular mechanisms of gene expression and regulation the principles of genetic engineering and their application in medicine. Summarize molecular concept of body defenses and their application in medicine. Outline the biochemical basis of environmental health hazards, biochemical basis of cancer and carcinogenesis; Familiarize with the principles of various conventional and specialized laboratory investigations and instrumentation, analysis and interpretation of a given data. Suggest experiments to support theoretical concepts and clinical diagnosis. Make use of conventional techniques/instruments to perform biochemical analysis relevant to clinical screening and diagnosis. Analyze and interpret investigative data. Demonstrate the skills of solving scientific and clinical problems and decision making. The knowledge acquired in biochemistry shall help the students to integrate molecular events with structure and function of the human body in health and disease. The students study Bio chemistry for a period of one year during 1st year of M.B.B.S. They are divided into 2 batches for Theory and practical classes conducted by all teaching faculty of the department. As per norms laid down by Medical Council of India, 240 hours are allocated in the first M.B.B.S. to teach biochemistry. Three hours per week is allotted to theory classes for the entire batch and 4 hours for practical to each batch. Seminars and group discussions involving participation of students are conducted every month. Periodic Internal Assessment tests both in theory & practical and viva voce are conducted. A minimum of 5 - 6 internal assessment tests are conducted throughout the year. A model theory & practical examination is conducted prior to the university examination in the month of June. The academic progress and attendance detail of each student is communicated to the parents in the months of December and June every year.
RESEARCH ACTIVITIES:
  1. Serum Magnesium in Acute Coronary Syndrome and its correlation with other serum parameters
  2. Blood biochemistry parameters in cancer chemotherapy
  3. Coagulation profile in Hypertensive Patients
  4. Lipid Profile in South Asian Population - A population profile
  5. Thyroid Profile in Pregnant Rural Women
  6. Thyroid Hormones and Psychiatric Illness - A correlative Study
  7. Blood Biochemistry in ART Therapy for HIV
  8. Coagulation Profile of patients with Diabetes Mellitus
  9. HbA1c values in Young South Asian Diabetics - A prospective Study

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